◀ Back to ANGPT2

ANGPT2 — EGF

Text-mined interactions from Literome

Wang et al., J Biol Chem 1999 : Nitric oxide did not affect either EGF receptor phosphorylation or Shc-Grb2 activation induced by either Ang II or EGF
Fujiyama et al., Circ Res 2001 : Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF) mediated EGF receptor transactivation
Frank et al., Biochem Biophys Res Commun 2001 : These data indicate that ROS mediate Ang II-induced EGF receptor transactivation , a critical mechanism for ERK dependent growth in VSMCs
Shah et al., Mol Pharmacol 2002 : Ang II increased the association of Pyk2 with Src and with the epidermal growth factor receptor (EGF-R)
Seshiah et al., Circ Res 2002 : These results suggest that c-Src, EGF receptor transactivation, phosphatidylinositol-3-kinase, and Rac play important roles in the sustained Ang II-mediated activation of vascular smooth muscle cell NAD ( P ) H oxidases and provide insight into the integrated signaling mechanisms whereby Ang II stimulation leads to activation of the growth related NAD ( P ) H oxidases
Mukhin et al., J Biol Chem 2004 : EGF receptor blockade attenuated ERK activation, but not NHE-1 activation by 5-HT and Ang II , suggesting that the EGF receptor and NHE-1 work in parallel to stimulate ERK activity in RASM cells, converging distal to the EGF receptor but at or above the level of Ras in the Ras-MEK-ERK pathway
Smith et al., Endocrinology 2006 (MAP Kinase Signaling System) : Stimulation of Ishikawa cells and human endometrial biopsy explants with 100 nm iloprost ( a PGI analog ) rapidly activated ERK1/2 signaling and induced the expression of proangiogenic genes, basic fibroblast growth factor, angiopoietin-1 , and angiopoietin-2, in an epidermal growth factor receptor (EGFR) dependent manner
Murasawa et al., Circ Res 1998 : In the present study, we report the involvement of epidermal growth factor receptor (EGF-R) in Ang II-induced extracellular signal regulated kinase ( ERK ) activation, c-fos gene expression, and DNA synthesis in cardiac fibroblasts