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ANGPT2 — NOS3

Text-mined interactions from Literome

Tojo et al., Kidney Int 2000 : The expressions of eNOS in cortical microvascular endothelium and DDAH in kidney are enhanced by Ang II acting on AT(1) receptors
Benndorf et al., Circ Res 2003 : We therefore investigated the effect of Ang II on VEGF induced Akt and eNOS phosphorylation
Bayraktutan et al., J Hypertens 2003 : To assess the effects of angiotensin II (ang II) and its receptors on nitric oxide ( NO ) production and endothelial NO synthase (eNOS) activity and expression with respect to rat aortic endothelial cell ( RAEC ) growth
Fernandez et al., Hypertension 2005 : In Ca ( 2+ ) -loaded neurons, Ang II-induced decreases in [ Ca ( 2+ ) ] i were attenuated by phospholipase C inhibition ( U73122 ) or nitric oxide ( NO ) synthase inhibition ( L-NMMA ) and were mimicked by the cGMP analogue 8-Br-cGMP
Yayama et al., Hypertension 2006 : In the in vitro experiments using aortic rings prepared from banded mice, Ang II produced significant increases in both forms of phosphorylated eNOS , as well as cGMP, and these effects were blocked by PD123319 and icatibant
Li et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2007 : Tanshinone II A could inhibit the negative effect of Ang- II on NO production and eNOS expression in PAEC
Zhong et al., Br J Pharmacol 2008 (Insulin Resistance) : In addition, Ang II diminished insulin stimulated phosphorylation of Akt ( at Ser ( 473 ) ) and eNOS ( at Ser ( 1177 ) ) and NO generation, effects which were reversed by ACE2 gene transfer and anti-MIF treatment in endothelial cells
Ratliff et al., Pediatr Res 2010 : ANG II regulates nNOS and eNOS expression and NOS activity in afferent arterioles of the developing kidney via AT1 and AT2 receptors
Kim et al., Am J Physiol Endocrinol Metab 2012 : Activation of mTOR/p70S6 kinase by ANG II inhibits insulin stimulated endothelial nitric oxide synthase and vasodilation