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EPHB2 — MDM2

Text-mined interactions from Literome

Halaschek-Wiener et al., Cell Signal 2004 (Carcinoma...) : Consistent with the Ras/Raf/MEK/ERK mediated control of Mdm2 , treatment of SW480 cells with the Ras inhibitor FTS caused a marked ( 80 % ) decrease in Mdm2, which itself would account for the increase in p53
Phelps et al., J Biol Chem 2005 : MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm ... Growth and survival factor activated Ras-Raf-MEK-ERK signaling can also regulate Hdm2 expression independently of p53, contributing to the pro-survival effect of these factors
Malmlöf et al., J Biol Chem 2007 : MEK-ERK mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes
Girnita et al., J Biol Chem 2007 : Beta-arrestin and Mdm2 mediate IGF-1 receptor stimulated ERK activation and cell cycle progression