Gene interactions and pathways from curated databases and text-mining

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GYS1 — PI3

Text-mined interactions from Literome

Egawa et al., Endocrinology 2000 (Insulin Resistance) : Recently, we have reported that the overexpression of a membrane targeted phosphatidylinositol (PI) 3-kinase ( p110CAAX ) stimulated p70S6 kinase, Akt, glucose transport, and Ras activation in the absence of insulin but inhibited insulin stimulated glycogen synthase activation and MAP kinase phosphorylation in 3T3-L1 adipocytes
Patti et al., Ann N Y Acad Sci 1999 (Diabetes Mellitus, Type 2...) : Similarly, activation of the hexosamine pathway by infusion of glucosamine also reduces insulin stimulated phosphorylation of IRS proteins, activation of PI3-kinase , and activation of glycogen synthase