Gene interactions and pathways from curated databases and text-mining

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CD40 — MMP12

Text-mined interactions from Literome

Wu et al., Biochem Biophys Res Commun 2000 : Induction and regulation of matrix metalloproteinase-12 by cytokines and CD40 signaling in monocyte/macrophages
Gotoh et al., J Rheumatol 2004 (Arthritis, Rheumatoid...) : CD40-CD154 interaction augments the expression of inflammatory cytokines and MMP in chondrocytes and contributes to an intrinsic process of cartilage degradation in RA
Oviedo-Orta et al., Immunology 2008 : Finally, we investigated whether CD40-CD40 ligand (CD40L) interactions were involved in T-cell stimulated MMP secretion from macrophages