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NFKB1 — PSMD10
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Fribley et al., Cancer Biol Ther 2006
(Neoplasms) :
Activation of the transcription factor
nuclear factor kappa B (NF-kappaB) , a key survival factor, is
dependent on the
26S proteasome
Higashitsuji et al., Biochem Biophys Res Commun 2007
:
Gankyrin did not
affect the
NF-kappaB DNA binding activity or nuclear translocation of RelA induced by TNFalpha in these cells
Chen et al., Cell Res 2007
:
Here we show that
p28(GANK) inhibits
NF-kappaB activity ... These results suggest that overexpression of
p28(GANK) prevents the nuclear localization and
inhibits the activity of
NF-kappaB/RelA
Dai et al., Cell Res 2009
(Carcinoma, Hepatocellular...) :
We also demonstrated that
p28(GANK) increases p38 mitogen activated protein kinase and Akt phosphorylation, and
inhibits nuclear factor kappa B (NF-kappaB) activation under ER stress, which in turn contributes to GRP78 upregulation
Wang et al., Circ Res 2010
:
Consistently, we found that genetic deletion of AMPKalpha2 in low-density lipoprotein receptor knockout ( LDLr ( -/- ) ) strain markedly increased
26S proteasome activity, IkappaB degradation,
NF-kappaB transactivation , NAD ( P ) H oxidase subunit overexpression, oxidative stress, and endothelial dysfunction, all of which were largely suppressed by chronic administration of MG132, a potent cell permeable proteasome inhibitor
Grisham et al., Methods Enzymol 1999
(Arthritis...) :
Inhibition of
NF-kappa B activation in vitro and in vivo : role of
26S proteasome