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IRF1 — TNFSF10

Text-mined interactions from Literome

Clarke et al., EMBO J 2004 (Breast Neoplasms...) : Our results identify a novel TRAIL mediated tumor suppressor activity of IRF-1 and suggest a mechanistic basis for the synergistic antitumor activities of certain retinoids and interferons
Papageorgiou et al., Cancer Biol Ther 2007 (Urinary Bladder Neoplasms) : Interferon-alpha induces TRAIL expression and cell death via an IRF-1 dependent mechanism in human bladder cancer cells ... Together, our results demonstrate that IFNalpha induces TRAIL expression via a STAT-1/IRF-1 dependent mechanism in human bladder cancer cells, and this induction of TRAIL plays an important role in IFNalpha induced cell killing
Tsuno et al., J Immunother 2009 (Adenocarcinoma...) : In IFN-alpha treated OVCAR3 cells, IRF9-RNAi inhibited transcription of TRAIL whereas Stat1-RNAi did not, suggesting that the transcription of TRAIL induced by IFN-alpha predominantly required IRF9