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ADD1 — FAS
Text-mined interactions from Literome
Gondret et al., J Lipid Res 2001
:
Moreover, overexpression of
ADD-1/SREBP-1 by adenoviral gene transfer
induces FAS in chicken adipocytes, where lipogenesis is normally low
Lacasa et al., J Biol Chem 2001
:
Fatty acid synthase (FAS) , a nutritionally regulated lipogenic enzyme, is transcriptionally
controlled by
ADD1/SREBP1c ( adipocyte determination and differentiation 1/sterol regulatory element binding protein 1c ), through insulin mediated stimulation of ADD1/SREBP1c expression
Kim et al., Biochem J 2001
:
Using adenoviral overexpression of a dominant negative form of adipocyte determination and differentiation factor 1 ( ADD1 ), a transcription factor that binds to the insulin-responsive E box, we demonstrated that
ADD1 was
required for Ang II regulation of the
FAS gene in 3T3-L1 adipocytes