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CCND1 — TMED7

Text-mined interactions from Literome

Schönthal et al., Exp Eye Res 1999 : However, the growth-inhibitory status of these components is clearly reversible : upon transduction with large T antigen, the expression of cyclin A, cyclin D , cdk2, and cdk4 is induced , whereas the expression of p21 and p27 is inhibited, and the cells proliferate
Zi et al., Proc Natl Acad Sci U S A 1999 (Carcinoma...) : Silibinin induced G1 arrest was associated with a marked decrease in the kinase activity of cyclin dependent kinases (CDKs) and associated cyclins because of a highly significant decrease in cyclin D1 , CDK4, and CDK6 levels and an induction of Cip1/p21 and Kip1/p27 followed by their increased binding with CDK2
Sánchez-Beato et al., Blood 1999 (Burkitt Lymphoma...) : We simultaneously studied them for p27, cyclin D3, cyclin D2, cyclin D1, and cyclin E expression, because it has been stated that high levels of expression of cyclin D1 or E lead to increased p27 levels in some cell types
Swarbrick et al., Mol Cell Biol 2000 (Breast Neoplasms) : In contrast, cyclin D-Cdk4 was not inhibited by His ( 6 ) -p27 in vitro or p27 ( Kip1 ) in vivo
Ding et al., J Biol Chem 2005 (Glioblastoma...) : We found that overexpression of wild-type FAK promoted exit from G ( 1 ) in monolayer cultures of glioblastoma cells, enhanced the expression of cyclins D1 and E while reducing the expression of p27 ( Kip1 ) and p21 ( Waf1 ), and enhanced the kinase activity of the cyclin D1-cyclin dependent kinase-4 (cdk4) complex
Paternot et al., Mol Endocrinol 2006 : By contrast, TSH repressed or did not induce cyclin D1 and p21, and it rather up-regulated p27
Kase et al., Int J Mol Med 2006 (Cell Transformation, Viral) : p27 ( KIP1 ) phosphorylation and cyclin D1 induction were inhibited by PD98059
York et al., Clin Cancer Res 2007 (Carcinoma, Renal Cell...) : PPARgamma is overexpressed in ACHN cells and barely detectable in 786-0 cells, and treatment with DIM-C-pPhtBu induces proteasome dependent degradation of cyclin D1 and variable effects on p21 and p27 expression in both cell lines
Chan et al., J Pathol 2008 (Carcinoma, Squamous Cell...) : This inhibitory phenomenon was associated with the reduced expressions of cyclin B1, cyclinD1 and cdc25B but increased expression of p27 ( Kip1 ) and p21 ( Cip1 )
Larrea et al., Mol Cell Biol 2008 : However, Src treatment led to tyrosine phosphorylation of p27 and catalytic activation of assembled cyclin D1-Cdk4-p27 complexes
Yu et al., Carcinogenesis 2009 (Carcinoma, Squamous Cell...) : Moreover, we demonstrated that the upregulation of AEG-1 could reduce the expression of p27 ( Kip1 ) and induce the expression of cyclin D1 through the AKT/FOXO3a pathway
Zou et al., Int J Mol Med 2009 (Carcinoma, Non-Small-Cell Lung...) : Western blotting showed that PI-103 induced down-regulation of cyclin D1 and E1 and simultaneously up-regulated p21 and p27 , associated with arrest in the G0-G1 phase of the cell cycle
Li et al., World J Gastroenterol 2009 (Stomach Neoplasms) : Macrophage MIF increases the proliferation of gastric cancer cells, induces the expression of cyclin D1 at the transcriptional level and inhibits the expression of p27 ( Kip1 ) at the post-transcriptional level via the PI3K/Akt pathway
Weber et al., J Biol Chem 1997 : Overexpression of dominant negative forms of Ras or RhoA completely blocked PDGF induced p27 ( KIP1 ) degradation, but only dominant negative Ras inhibited cyclin D1 protein expression