Gene interactions and pathways from curated databases and text-mining

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HMOX1 — SOD1

Text-mined interactions from Literome

Frankel et al., J Cell Physiol 2000 : Role of heme oxygenase-1 in the regulation of manganese superoxide dismutase gene expression in oxidatively challenged astroglia
Turkseven et al., Am J Physiol Heart Circ Physiol 2005 (Diabetes Mellitus, Experimental) : Upregulation of HO-1 expression by intermittent administration of cobalt protoporphyrin, an inducer of HO-1 protein and activity, resulted in a robust increase in EC-SOD but no significant change in Cu-Zn-SOD
Iori et al., Life Sci 2008 : HO-1 protein expression in HUVECs exposed to 20 mM of glucose was increased in the presence of 20 U/ml superoxide dismutase ( SOD )
Luz et al., J Immunol 2012 (Leishmaniasis, Visceral) : Furthermore, upregulation of HO-1 by cobalt protoporphyrin IX diminished the production of TNF-a and reactive oxygen species by infected murine macrophages and increased Cu/Zn superoxide dismutase expression in human monocytes
Tsapenko et al., American journal of physiology. Renal physiology 2012 : One week after AVF creation, there was increased production of superoxide anion accompanied by decreased total superoxide dismutase ( SOD ) and Cu/Zn SOD activities and induction of the redox-sensitive gene heme oxygenase-1
Chandra-Kuntal et al., Breast Cancer Res Treat 2013 (Breast Neoplasms) : The DATS mediated induction of heme oxygenase-1 was partially attenuated by overexpression of Mn-SOD