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KCNH4 — PTGS2

Text-mined interactions from Literome

Guo et al., J Biol Chem 2001 (Cell Transformation, Neoplastic...) : Bombesin stimulation of COX-2 expression requires an increase in [ Ca ( 2+ ) ] ( i ), activation of extracellular signal regulated kinase ( ERK ) -1 and -2 and p38 ( MAPK ), and increased activation and expression of the transcription factors Elk-1 , ATF-2, c-Fos, and c-Jun
Zhang et al., International journal of endocrinology 2013 : We first investigated the effects of Elk-1 on COX-2 transcriptional regulation and expression in INS-1 cells ... Our results demonstrate that Elk-1 efficiently upregulates COX-2 expression at least partly through directly binding to the -82/-69 region of COX-2 promoter