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CCR7 — TNF

Text-mined interactions from Literome

Vecchi et al., J Leukoc Biol 1999 : TNF-alpha down-regulated CC chemokine receptor (CCR)1, CCR2, and CCR5 and up-regulated CCR7 mRNA levels, in agreement with functional data
Sato et al., J Immunol 2000 : Stimulation of mature DCs with TGF-beta 1 also enhanced TNF-alpha induced down-regulation of the expressions of CCR-1, CCR-3, CCR-5, CCR-6, and CXCR-4, and chemotaxis to their respective ligands, while this stimulation suppressed TNF-alpha induced expression of CCR-7 and chemotactic migratory ability to MIP-3 beta
Croitoru-Lamoury et al., Glia 2003 : Moreover, TNFalpha and IL-1beta significantly increase BOB/GPR15, CCR2 , and V28/CX3CR1 mRNA levels in both models
Boislève et al., J Invest Dermatol 2004 (MAP Kinase Signaling System) : CCR7 expression was strongly dependent on TNF-alpha in the case of DNCB, however, neutralization of TNF-alpha only partially reduced CCR7 expression upon NiSO ( 4 ) treatment
Ponte et al., Stem Cells 2007 : TNFalpha increases CCR2, CCR3 , and CCR4 expression ( as opposed to that of CXCR4 ), together with RANTES membrane binding
Catley et al., IDrugs 2010 (Asthma...) : This conference report highlights selected presentations on mAb treatments for asthma, including targeting IL-5, IL-13, IL-9 and TNFa , CCR3 inhibitors , histamine H4 receptor inhibition, novel mouse models of COPD and inhaled antisense asthma therapies