Gene interactions and pathways from curated databases and text-mining

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CCR6 — IL10

Text-mined interactions from Literome

Dieu-Nosjean et al., J Immunol 2001 : IL-10 induces CCR6 expression during Langerhans cell development while IL-4 and IFN-gamma suppress it ... The effect of IL-10 was reversible and upon IL-10 withdrawn, CCR6 was lost concomitantly to final LC differentiation ... In addition, IL-10 induced the expression of CCR6 and responsiveness to CCL20 in differentiated monocytes that preserve their ability to differentiate into mature DC
Jiang et al., Chin Med J (Engl) 2009 (Embryo Loss) : Expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model, selectively induced by IL-4 and IL-10 , regulates the embryo resorption rate ... This study aimed to observe whether IL-4 and IL-10 may regulate the expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model and to explore the role of CCR3, CCR5, CXCR3 in immune tolerance in pregnancy
Tian et al., Invest Ophthalmol Vis Sci 2012 (Behcet Syndrome) : VitD3 was able to inhibit the gene expression of RORC, IL-17, IL-23R, CCR6 , and Th1 cell differentiation, but upregulated IL-10 expression ... VitD3 was able to inhibit the gene expression of RORC, IL-17, IL-23R, CCR6 , and Th1 cell differentiation, but upregulated IL-10 expression