Gene interactions and pathways from curated databases and text-mining

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LEP — SETD2

Text-mined interactions from Literome

Aleffi et al., Am J Physiol Gastrointest Liver Physiol 2011 (Neovascularization, Pathologic) : Both leptin and PDGF increased the expression of HIF-1a and VEGF in HSC
Yu et al., Environ Sci Technol 2012 : Overall, this study indicates that hypoxia, possibly via HIF-1 induced leptin expression, modulates sex steroid synthesis by acting directly on steroidogenic gene expression