Gene interactions and pathways from curated databases and text-mining

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CD80 — HNRNPF

Text-mined interactions from Literome

Li et al., Scand J Immunol 2000 : Lipopolysaccharide (LPS) treatment induced the upregulation of CD40, CD80 , CD86 and the T-cell stimulatory capacity in IL-4-DCs and, to a lesser extent, in the IL-7-DCs whereas GM-CSF-DCs responded very poorly to such treatment
Frleta et al., J Immunother 2003 : When purified DCs were co-cultured in vitro with antigen-specific T cell hybridomas, the DCs had lower expression of total MHC class II and `` complex, '' but did not reduce their CD80 and CD86 expression
Veckman et al., J Leukoc Biol 2004 : Stimulation of DCs with S. pyogenes resulted in strong expression of DC costimulatory molecules CD80 , CD83, and CD86 accompanied with a T helper cell type 1 ( Th1 ) cytokine and chemokine response
Carrasco et al., J Gen Virol 2004 : Stimulation of DCs with IFN-alpha/TNF-alpha or polyinosinic-polycytidylic acid ( pIC ) induced phenotypic maturation with increased MHC and CD80/86 expression, both with mock treated and infected DCs
Yang et al., Chin J Cancer 2004 (Carcinoma, Hepatocellular...) : DCs up-regulated the expression of CD1a ( 55.0 % ), CD11c ( 98.6 % ), CD86 ( 86.1 % ), CD80 ( 66.1 % ), and HLA-DR ( 88.9 % ) after cultured for 5 days
Koh et al., J Korean Med Sci 2004 (Asthma...) : BCG treated DCs enhanced significantly the expressions of CD80 , CD86, and CD40, and the productions of IL-12 and IL-10
Wong et al., Immunology 2005 (Cell Transformation, Viral...) : Interaction of adult DCs with necrotic but not early apoptotic LCLs resulted in high expression of DC costimulatory molecules ( CD80/CD86 ) and activation markers ( CD83 ), production of both proinflammatory and anti-inflammatory cytokines ( tumour necrosis factor-alpha, interleukin-10 ), and strong T-cell stimulating activities
Messmer et al., Mol Med 2004 (Leukemia, Lymphocytic, Chronic, B-Cell) : Furthermore, B-CLL-DCs generated from the 2 CLL subgroups up-regulated MHC-II, CD80 , CD86, CD83, CD40, and CD54 and down-regulated CD206 in response to stimulation with a cocktail of cytokines ( CyC ) and secreted increased levels of tumor necrosis factor alpha, interleukin (IL)-8, IL-6, IL-12 ( p70 ), and RANTES in a manner typical of mature normal-DCs
Yamazaki et al., Proc Natl Acad Sci U S A 2006 (Graft vs Host Disease) : Likewise, DCs and not spleen cells were effective in sustaining expression of the transcription factor Foxp3 in Tregs, but neither IL-2 nor CD80/86 was required for this effect in the cultures
Jiga et al., Transplantation 2007 : We showed previously that dendritic cells (DCs) treated with mitomycin C ( MMC ) tolerize allogeneic T cells in vitro and this might be mediated by downregulation of CD80 , CD86, and ICAM-1
Wang et al., J Immunol 2007 : LPS stimulation of splenic DCs in vivo resulted in prolonged CD80/CD86 expression on WSX-1-deficient DCs over wild-type DCs
Yang et al., Zhonghua Zhong Liu Za Zhi 2007 (Carcinoma, Hepatocellular...) : AdVHBsAg-DC was able to upregulate CD1a, CD11c, CD80 , CD86 and HLA-DR. Autologus T cell proliferation induced by AdVHBsAg-DCs was significantly higher than that in DC control group and LacZ-DC group ( P < 0.05 )
Tian et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2008 (Leukemia, Promyelocytic, Acute) : The results indicated that in experiment groups, the cells had dendritic appearance and cytogenetic characteristics of APL ; expression of CD1a, CD83, CD80 , CD86, HLA-DR and CD1d as well as level of IL-12 obviously increased ; the MLR and CTL effects were significant, but increase of CD1a expression in HL60-DCs did not show statistical difference from control and blank control groups
Usui et al., Arch Ophthalmol 2009 (Autoimmune Diseases...) : Regulatory DCs expressed comparable levels of major histocompatibility complex class II molecules but reduced levels of CD80 , CD86, and CD40 compared with mature DCs
Jin et al., J Cosmet Dermatol 2009 : UVB irradiation was able to inhibit the ability of DCs to stimulate the proliferation of lymphocytes and surface expressions of CD80 , CD86, HLA-DR, and CD40 on DCs in a dose dependent manner
Qiu et al., Int Immunopharmacol 2012 : The expression levels of co-stimulatory molecules ( CD80 , CD86 and CD83 ) and MHC-II class molecule were lower in the RelB shRNA-DCs than in the mDCs and silencing control DCs
Sun et al., Journal of biomedical research 2012 : The results showed that monocyte derived DCs induced by either SLE serum or exogenous IL-10 reduced the expression of human leukocyte antigen ( HLA ) -DR and CD80 , decreased IL-12p40 level, and increased IL-10 level, and exhibited an impaired capacity to stimulate allogenic T-cell proliferation