Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MEF2C

Text-mined interactions from Literome

Cavanaugh et al., J Neurosci 2001 : In contrast to ERK1/2, ERK5 strongly activated the transcriptional activity of myocyte enhancer factor 2C (MEF2C) in pheochromocytoma 12 ( PC12 ) cells and was required for neurotrophin stimulation of MEF2C transcription in both PC12 cells and cortical neurons
Zhao et al., Mol Cell Biochem 2009 : Activation of myocyte enhancer factor-2C (MEF2C) by ERK5 was inhibited by PD98059
Zhao et al., J Cell Biochem 2010 (Hypertrophy) : These data provide evidence that PKCepsilon dependent ERK5 phosphorylation and nucleocytoplasmic traffic mediates Ang II-induced MEF2C activation and cardiomyocyte hypertrophy