Gene interactions and pathways from curated databases and text-mining

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ANK1 — SETD2

Text-mined interactions from Literome

Zaka et al., J Bone Miner Res 2009 : Oxygen tension regulates the expression of ANK ( progressive ankylosis ) in an HIF-1 dependent manner in growth plate chondrocytes ... The data suggest that ANK expression and function in vitro and in vivo are repressed in hypoxic environments and that the effect is regulated by HIF-1
Skubutyte et al., Arthritis Rheum 2010 (Calcinosis) : Transfections were performed to determine the effect of HIF-1/2 on ANK promoter activity ... However, silencing of HIF-1a and HIF-2a resulted in increased ANK expression and up-regulation of promoter activity ... Overexpression of HIF-1a and HIF-2a in nucleus pulposus cells resulted in a significant suppression of ANK promoter activity