Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Complex of E2F4-EP300
→
TGFB1
(decreases)
Evidence: TGF-beta signaling did not compete with E2F-4 for binding to TIE/E2F, but reduced p300 co-immunoprecipitating with E2F-4. Therefore, TGF-beta signaling may suppress c-myc promoter activity by dissociating p300 from E2F-4.
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *