Gene interactions and pathways from curated databases and text-mining

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IRF6 — MIPEP

Text-mined interactions from Literome

Xavier et al., Am J Respir Cell Mol Biol 1999 : To investigate whether LPS induced TNF-alpha release is related to other inflammatory mediators from the same cell type, we examined effects of LPS stimulation on macrophage inflammatory protein (MIP)-2 production by alveolar epithelial cells, and then examined the relationship between TNF-alpha and MIP-2 production ... These results suggest that LPS induced MIP-2 release from alveolar epithelial cells may be mediated in part by TNF-alpha from the same cell type
Olszyna et al., J Infect Dis 2000 (Endotoxemia) : Sixteen healthy subjects were intravenously injected with lipopolysaccharide (LPS), once with placebo and once with recombinant human interleukin (IL)-10 ( 25 microgram/kg ), to determine the effect of IL-10 on LPS induced production of macrophage inflammatory protein (MIP)-1alpha , MIP-1beta, and monocyte chemoattractant protein (MCP)-1
Liaudet et al., Ann Surg 2002 (Disease Models, Animal...) : Inosine downregulated the LPS induced expression of TNF-alpha, IL-1beta, IL-6 and MIP-2 and tended to reduce MIP-1alpha, whereas it enhanced the production of IL-4
Calkins et al., J Endotoxin Res 2002 (Disease Models, Animal...) : In summary, LPS induces IL-1beta and MIP-2 expression in the lung and liver, both of which are IL-1 dependent
Menten et al., J Leukoc Biol 2002 (Disease Models, Animal...) : Moreover, upon stimulation with lipopolysaccharide (LPS) or virus, ESb-MP cells themselves produce significant amounts of MIP-1 ( approximately 200 ng/ml )
Kim et al., Mol Immunol 2003 : We show here that the MIP-2 promoter is transcriptionally activated in a macrophage cell line RAW 264.7 by LPS through a sequence located between -450 and -54 and this region contains two copies of activator protein-1 (AP-1) and one copy of nuclear factor-kappaB (NF-kappaB) binding site
Uchiyama et al., Clin Exp Pharmacol Physiol 2004 (Respiratory Distress Syndrome, Adult) : Furthermore, TMG attenuated the LPS induced increase in pulmonary expression of KC, MIP-1alpha and MCP-1 at both the transcriptional and translational levels
Ellaban et al., Cell Immunol 2004 (Cecal Diseases...) : Production of IL-10 and the IL-1 receptor antagonist, MIP-2 , and MCP-1 in response to LPS stimulation was equivalent to the amount produced by naive macrophages
Lucchi et al., J Reprod Immunol 2007 : LPS induced time dependent expression and secretion of IL-8, macrophage inflammatory protein (MIP)-1alpha and MIP-1beta from ST cells and an upregulation of ICAM-1
Yeh et al., Life Sci 2007 (Edema...) : Hesperidin downregulate the LPS induced expression of TNF-alpha, IL-1 beta, IL-6, KC, MIP-2 , MCP-1, and IL-12
Sha et al., Eur J Pharmacol 2007 (Disease Models, Animal...) : Intravenous administration of TAK-242 to mice 1 h before LPS challenge dose-dependently inhibited LPS induced increases in serum levels of TNF-alpha, IL-1beta, IL-6, IL-10, MIP-2 , and NO metabolites
Martin et al., Cell Immunol 1991 : In contrast, PGE1 inhibits LPS induced JE, MIP-1 alpha, and MIP-1 beta mRNA expression and this inhibition is partially dependent on a cAMP mediated pathway of signal transduction
Berchtold et al., BMC immunology 2008 : By using stably transfected RAW264.7 macrophages overexpressing IFIT-2 we found that IFIT-2 inhibits selectively LPS induced expression of TNF-alpha, IL-6, and MIP-2 but not of IFIT-1 or EGR-1
Moon et al., Respir Res 2009 (Acute Lung Injury...) : A pretreatment with RGDS inhibited LPS induced increases in neutrophil and macrophage numbers, total protein levels and TNF-alpha and MIP-2 levels, and matrix metalloproteinase-9 activity in bronchoalveolar lavage (BAL) fluid at 4 or 24 h post-LPS treatment
Arranz et al., Age (Dordrecht, Netherlands) 2010 (Inflammation) : Chemokine responses in regard to KC, MCP-1, MIP1ß, and RANTES were more variable, though similar secretion of LPS induced KC and MCP-1 and ConA induced MCP-1, MIP-1ß , and RANTES was found in long lived and middle aged mice
Larmonier et al., Inflamm Bowel Dis 2011 (Disease Models, Animal) : Curcumin attenuated lipopolysaccharide (LPS) stimulated expression and secretion of macrophage inflammatory protein (MIP)-2 , interleukin (IL)-1ß, keratinocyte chemoattractant ( KC ), and MIP-1a in colonic epithelial cells ( CECs ) and in macrophages
Lee et al., J Nutr Biochem 2011 : Enzyme linked immunosorbent assay results showed that lipopolysaccharide (LPS) induces the expression of monocyte chemotactic protein-1 (MIP-1), tumor necrosis factor-a, stromal cell derived factor-1, and MIP-1a , and this induction may be repressed by GBE treatment due to TLR4 blockade
Trummer-Menzi et al., Pediatric pulmonology 2012 (Disease Models, Animal...) : At T : 0 hr, LPS + MV + O ( 2 ) increased gene expression of pro-inflammatory MIP-2
Weinberger et al., Neonatology 2013 (Hyperbilirubinemia, Neonatal...) : Bilirubin increased basal production of IL-8 and IL-1ß, but downregulated LPS induced generation of IL-8 and MIP-1ß
Sakai et al., Cytokine 1997 : These data suggest that MIP-2 might be induced by a direct effect of LPS and in part indirect one via initial induction of other cytokines such as TNF-alpha, leading a tendency of biphasic pattern
Ishii et al., J Neurooncol 1998 (Astrocytoma...) : However, MIP-1alpha production was increased in three cell lines by stimulation with lipopolysaccharide (LPS) and 5 cell lines by stimulation with phorbol-12myristate-13-acetate ( PMA )