UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CDK2 — RPTOR

Pathways - manually collected, often from reviews:

NCI Pathway Database mTOR signaling pathway: mTORC1 complex (MTOR-MLST8-RPTOR) → CDK2/Cyclin E1 complex (CDK2-CCNE1) (modification, activates)
Mayer et al., Genes Dev 2004
Evidence: mutant phenotype, assay