Bastian et al., Blood 1999
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Regulation of the megakaryocytic glycoprotein IX promoter by the oncogenic Ets transcription factor Fli-1 ... In this study, transient cotransfection of several GPIX promoter/reporter constructs into 293T kidney fibroblasts with a Fli-1 expression vector shows that the oncogenic protein Fli-1 can transactivate the GPIX promoter when an intact GPIX Ets site is present
Eisbacher et al., Mol Cell Biol 2003
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Overexpression of Fli-1 induced the expression of the endogenous GPIX and GPIbalpha genes as measured by Northern blot and fluorescence activated cell sorter analysis
Kostyak et al., Frontiers in bioscience : a journal and virtual library 2007
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GATA-1 and Fli-1 interactions result in heightened GPIX and GPIb ( 2 components of von Willebrand Factor (vWF) receptor ) expression, while GATA-1, RUNX1 and core binding factor beta interactions result in improved alphaIIb promoter activity