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NOS3 — PFN1
Text-mined interactions from Literome
Kasina et al., Nitric Oxide 2006
:
A decrease in the level of nitroprofilin in PDBu treated platelets in the presence of inducible nitric oxide synthase inhibitor, 1400W, was observed suggesting that
profilin nitration is
mediated by PI 3-kinase dependent activation of inducible
nitric oxide synthase
Jin et al., PloS one 2012
(Inflammation) :
Our findings reveal that ACE2 deficiency worsens Ang II-mediated aortic inflammation and peroxynitrite production associated with the augmentation of
profilin-1 expression and the
activation of the
Akt-ERK-eNOS signaling, suggesting potential therapeutic approaches by enhancing ACE2 action for patients with vascular diseases