Sopjani et al., Mol Membr Biol 2010
:
According to confocal microscopy and Western Blotting, AICAR ( 1 mM ), phenformin ( 1 mM ) and A-769662 ( 10 microM ) enhanced the SGLT1 protein abundance in the cell membrane of Caco2 cells suggesting that AMPK activity may increase membrane translocation of SGLT1 Banerjee et al., J Mol Cell Cardiol 2010
(Cardiomyopathies) :
Increased AMPK activity leads to upregulation of SGLT1 , which in turn mediates increased cardiac glucose uptake