Gene interactions and pathways from curated databases and text-mining

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CTGF — NTRK1

Text-mined interactions from Literome

Wahab et al., J Am Soc Nephrol 2005 : Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA
Wang et al., Am J Physiol Cell Physiol 2009 (Cardiomegaly...) : In addition, these CTGF effects were through the tyrosine kinase A (TrkA) receptor with tyrosine kinase activity, which has previously been implicated in CTGF signaling : TrkA was phosphorylated by CTGF, and a specific TrkA blocker abrogated CTGF induced effects on hypertrophy and apoptosis