Gene interactions and pathways from curated databases and text-mining

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CD72 — CD79B

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Li et al., Arthritis Rheum 2008 (Autoimmune Diseases) : Biochemical analyses indicated that in anergic B cells, CD72 dominantly down-regulated BCR signaling to limit the antigen induced elevation in [ Ca2+ ] i and the activation of NFATc1, NF-kappaB, MAPK, and Akt ... Mechanistically, CD72 was associated with, and regulated, the molecular adaptor Cbl-b in anergic B cells, suggesting that Cbl-b may play a role in mediating the negative effects of CD72 on BCR signaling
Xu et al., J Immunol 2013 (Autoimmune Diseases...) : We further demonstrated that Cd72(c) is a hypofunctional allele in BCR signal inhibition and that CD72 deficiency induces severe autoimmune disease in the presence of Fas ( lpr )
Adachi et al., J Immunol 1998 : Moreover, cross linking of B cell Ag receptor (BCR) enhances both tyrosine phosphorylation of CD72 and association of CD72 with SHP-1 in B cell line WEHI-231