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IFNG — PLCG2

Text-mined interactions from Literome

Chang et al., J Biol Chem 2002 : Thus, in NCI-H292 epithelial cells, IFN-gamma activates PLC-gamma2 via an upstream tyrosine kinase to induce activation of PKC-alpha and c-Src or Lyn, resulting in activation of STAT1alpha, and GAS in the ICAM-1 promoter, followed by initiation of ICAM-1 expression and monocyte adhesion
Tassi et al., J Immunol 2005 (Herpesviridae Infections) : Why PLCgamma2 is more important than PLCgamma1 for NK cell activation and whether PLCgamma2 is also critical for NK cell development, secretion of IFN-gamma , and clearance of viral infections in vivo is not known