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CTNNB1 — WT1

Text-mined interactions from Literome

Amini Nik et al., Int J Cancer 2005 (Fibroma) : Finally, we investigated a possible role of beta-catenin on WT1 regulation and vice versa ... Overexpression of different beta-catenin mutants in the HEK293T cell line did not modulate WT1 promoter activity and WT1 did not affect beta-catenin /TCF transcriptional activity in this cell line
Chang et al., Development 2008 : Wt1 negatively regulates beta-catenin signaling during testis development ... As Wt1 conditional knockout in Sertoli cells causes similar phenotypes to our stabilized beta-catenin mutants, we then investigated the relationship of Wt1 and beta-catenin in Sertoli cells and found Wt1 inhibits beta-catenin signaling in these cells during testis development