Gene interactions and pathways from curated databases and text-mining

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MAFA — NEUROD1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Raum et al., Mol Cell Biol 2010 : Further support for the importance of R3 was also shown, as the islet regulators Nkx6.1 and Pax6, but not NeuroD1 , activated MafA in gel shift, chromatin immunoprecipitation ( ChIP ), and transfection assays and in vivo mouse knockout models
Aguayo-Mazzucato et al., Diabetologia 2011 : Similar overexpression of MAFA resulted in increased Neurod1 , Nkx6-1, Gck and Glp1r mRNAs and no change in insulin content but, importantly, acquisition of glucose-responsive insulin secretion