Gene interactions and pathways from curated databases and text-mining

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DCC — NTN4

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Geisbrecht et al., J Biol Chem 2003 : Since netrin binds heparin, our results suggest that interactions between DCC and heparin are probably mediated by netrin
Kim et al., J Neurochem 2005 : Specific ubiquitin-proteasome inhibitors prevented the netrin induced DCC cleavage and decrease of cell surface DCC
Furne et al., Proc Natl Acad Sci U S A 2008 : In primary neuronal culture, in mice or in chick embryos, netrin-1 inhibits the proapoptotic activity of DCC in developing commissural neurons