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NOS3 — TGFB1

Text-mined interactions from Literome

Oyadomari et al., Nitric Oxide 2001 (Diabetes Mellitus, Experimental) : TGF-beta1 induced eNOS and AS mRNAs in human umbilical vein endothelial cells but inhibited the proliferation of HUVEC ... These results indicate that eNOS and AS are coinduced in the aorta in early stages of STZ induced diabetic rats and that the induction is mediated by TGF-beta1
Saura et al., Circ Res 2002 : Smad2 mediates transforming growth factor-beta induction of endothelial nitric oxide synthase expression
Schini et al., Eur J Pharmacol 1992 : The induction of nitric oxide synthase activity is inhibited by TGF-beta 1 , PDGFAB and PDGFBB in vascular smooth muscle cells
Sanders et al., Hypertension 2004 (Chronic Disease...) : A balance is struck between TGF-beta1 and NOS3 as salt intake varies and creates a negative feedback loop, because TGF-beta1 increased expression of NOS3 and NO inhibited production of TGF-beta1 in healthy rats
Boche et al., Neurobiol Dis 2006 (Chronic Disease...) : In contrast, inhibition of TGFbeta1 activity using an adenovirus expressing decorin induces severe cerebral inflammation, expression of inducible nitric oxide synthase and acute neuronal death in prion diseased animals only
Watanabe et al., Br J Pharmacol 2006 : ATP induced Ca2+ transients as well as eNOS protein expression were not affected by TGFbeta1 in BAECs
Vyas-Read et al., Am J Physiol Lung Cell Mol Physiol 2007 : TGF-beta1 ( 50 pM ) suppressed eNOS expression by more than 60 % and activity by 83 % but did not affect iNOS expression or activity
Hamby et al., Prostaglandins Other Lipid Mediat 2008 : TGF-beta1 reduces the heterogeneity of astrocytic cyclooxygenase-2 and nitric oxide synthase-2 gene expression in a stimulus independent manner
Koide et al., Hypertension 1994 : These findings suggest that interferon gamma directly induces the expression of the inducible nitric oxide synthase gene, whereas tumor necrosis factor-alpha and interleukin-1 beta induce it, at least in part, via the induction of intermediary protein ( s ), and that transforming growth factor-beta 1 inhibits cytokine induced nitric oxide production by blocking the posttranscriptional synthesis of inducible nitric oxide synthase
Inoue et al., Arterioscler Thromb Vasc Biol 1995 : Molecular regulation of the bovine endothelial cell nitric oxide synthase by transforming growth factor-beta 1 ... In conclusion, TGF beta 1 increases ecNOS expression associated with an increase in production of NO in BAEC
Goureau et al., Proc Natl Acad Sci U S A 1993 : Differential regulation of inducible nitric oxide synthase by fibroblast growth factors and transforming growth factor beta in bovine retinal pigmented epithelial cells : inverse correlation with cellular proliferation
Vincent et al., Glia 1997 : Inhibition of endotoxin induced nitric oxide synthase production in microglial cells by the presence of astroglial cells : a role for transforming growth factor beta
Mabley et al., J Endocrinol 1997 : Transforming growth factor beta 1 prevents cytokine mediated inhibitory effects and induction of nitric oxide synthase in the RINm5F insulin containing beta-cell line
Poppa et al., Arterioscler Thromb Vasc Biol 1998 : An important role for transforming growth factor (TGF)-beta1 in regulating eNOS expression was suggested by the ability of a TGF-beta1 neutralizing antibody to limit induction of eNOS at the wound edge