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HMOX1 — HPX

Text-mined interactions from Literome

Sung et al., Antioxid Redox Signal 2000 : A role for Cu ( I ) in the regulation of HO-1 and MT-1 ( Sung et al., 1999 ) by hemopexin supports the participation of electron transport processes at the cell surface as does competition by the reductase activator, ferric citrate, which inhibits the induction of MT-1 and HO-1 mRNA by heme-hemopexin
Smith et al., Antioxid Redox Signal 2000 : Heme oxygenase-1 (HO-1) , transferrin, the transferrin receptor, and ferritin are regulated by heme-hemopexin ... Redox processes at the cell surface, which generate cuprous ions, are involved in the regulation of the MT-1 and HO-1 genes by heme-hemopexin before heme catabolism and intracellular release of iron
Escriba et al., DNA Cell Biol 2002 : Hexamethylene-bisacetamide ( HMBA ), which induces differentiation and activates protein kinase C ( PKC ), synergistically augments the induction of both MT-I and MT-II mRNAs in response to heme-hemopexin , but attenuates the induction of HO-1
Flaherty et al., Biometals 2008 : Consistent with this, when the acidification of endosomes is prevented by bafilomycin then heme oxygenase-1 induction by heme-HPX no longer occurs
Li et al., J Cereb Blood Flow Metab 2009 (Disease Models, Animal...) : Taken together, these data show that HPX protects against heme induced toxicity and oxidative stress and that HO1 is required
Hunt et al., J Cell Physiol 1996 : Moreover, the binding of heme-hemopexin to the cells stimulates the expression of heme oxygenase-1 , metallothionein-1, and ferritin