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CXCL10 — IL1B

Text-mined interactions from Literome

Sauty et al., J Immunol 1999 : We found that IFN-gamma, but not TNF-alpha or IL-1 beta , strongly induced IP-10 , Mig, and I-TAC mRNA accumulation mainly in NHBEC and that TNF-alpha and IL-1 beta synergized with IFN-gamma induction in all three cell types
Frangogiannis et al., Cell Tissue Res 2000 (Endotoxemia) : TNF-alpha, IL-1 beta , and M-CSF are potent inducers of IP-10 in canine endothelial cells and may indirectly mediate lymphocyte chemotaxis and activation in inflammatory processes
Cheng et al., J Immunol 2002 : The eotaxin/CCL11-suppressive effect on endothelial cells was not seen on IL-1beta induced IL-8/CXCL8 release
Méndez-Samperio et al., J Interferon Cytokine Res 2002 : In addition, the specificity of this inhibition was demonstrated by the inability of herbimycin-A to block in a significant manner IL-1 beta induction of CXCL-8
McLoughlin et al., J Immunol 2004 (Peritonitis) : Moreover, when complexed with IL-6, both isoforms specifically inhibited the IL-1 beta induced secretion of CXCL8
Davis et al., Neurosci Lett 2004 : Furthermore, we observed that LPS + IL-1beta stimulated CXCL10 production is inhibited in human A172 astroglia exposed to chronic 50 mM ethanol
Dajotoy et al., J Leukoc Biol 2004 (Crohn Disease) : TNF-alpha but not IL-1beta enhanced the IFN-gamma induced production of MIG and IP-10
Omari et al., Brain 2005 (Hypertrophy...) : CXCL8 and CXCL1 production by human astrocytes at both the RNA and protein levels could be induced by interleukin (IL)-1beta, while CXCL10 was induced by both IL-1beta and interferon-gamma
Dragon et al., Am J Physiol Lung Cell Mol Physiol 2007 : IL-17 enhances IL-1beta mediated CXCL-8 release from human airway smooth muscle cells ... In this study, we evaluated whether IL-17 could enhance IL-1beta mediated CXCL-8 release from human airway smooth muscle cells ( HASMC ) and investigated the upstream and downstream signaling events regulating the induction of CXCL-8
Yeruva et al., Int J Colorectal Dis 2008 (Adenocarcinoma...) : NF-kappaB dependent synergistic regulation of CXCL10 gene expression by IL-1beta and IFN-gamma in human intestinal epithelial cell lines ... Real-time PCR and ELISA experiments using a specific NF-kappaB inhibitor and transfection experiments with a NF-kappaB binding defective CXCL10 promoter construct revealed that the induction of CXCL10 by IL-1beta and its synergism with IFN-gamma is NF-kappaB dependent ... These data demonstrate that in colonic epithelial cells, depending on the cellular context and utilizing the NF-kappaB pathway, IL-1beta alone and/or in synergism with IFN-gamma may play a major role in the induction of CXCL10
Johnston et al., Br J Dermatol 2008 (Chronic Disease...) : In vitro, both leptin and resistin could induce CXCL8 and tumour necrosis factor-alpha production by blood monocytes, and leptin could additionally induce IL-1beta and IL-1 receptor antagonist production
Hosokawa et al., J Periodontal Res 2009 (Periodontitis) : Human gingival fibroblasts produced CXCL10 protein upon stimulation with interleukin-1beta , tumor necrosis factor-alpha and interferon-gamma
Charron et al., J Biol Chem 2009 (Inflammation) : Hypoxia enhanced interleukin-1beta induced interleukin-8 ( CXCL8 ) production in A549 cells and decreased the ability of dexamethasone to suppress the CXCL8 production
Sunil et al., Int J Colorectal Dis 2010 : Influence of NFkappaB inhibitors on IL-1beta induced chemokine CXCL8 and -10 expression levels in intestinal epithelial cell lines : glucocorticoid ineffectiveness and paradoxical effect of PDTC ... Il-1beta stimulated CXCL8 and CXCL10 mRNA and protein expression and was studied in Caco-2 and HT29 cells in the presence and absence of the NFkappaB inhibitors by quantitative real-time polymerase chain reaction and enzyme linked immunosorbent serologic assay, respectively
Shultz et al., J Interferon Cytokine Res 2009 : In contrast to IFN-gamma, IL-1beta induces ip-10 expression rapidly but transiently, by activating classical NF-kappaB and increasing the synthesis of IRF1 ... Together, IL-1beta and IFN-gamma induce ip-10 synergistically ... IFN-gamma does not affect the transient activation of classical NF-kappaB by IL-1beta and synergistic induction of ip-10 expression by IFN-gamma and IL-1beta occurs even after the activation of classical NF-kappaB has returned to basal levels
Marotte et al., Rheumatology (Oxford) 2010 (Arthritis, Experimental...) : GTE ( 2.5-40 microg/ml ) inhibited IL-1beta induced MCP-1/CCL2 ( 10 ng/ml ), RANTES/CCL5, GROalpha/CXCL1 and IL-8/CXCL8 production in human RA synovial fibroblasts ( P < 0.05 )
Olaru et al., J Invest Dermatol 2010 (Staphylococcal Skin Infections) : IL-1alpha and IL-1beta increased mRNA production and protein secretion of the neutrophil chemotactic CXCL1, CXCL2 , and IL-8 in keratinocytes
Földes et al., PloS one 2010 : Expression of downstream TLR signalling pathways was demonstrated in hESC, and IL-1beta , TNFalpha and INFgamma, which bypass the TLRs, stimulated CXCL8 release