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LRRC2 — MYLIP
Text-mined interactions from Literome
Liu et al., BMC systems biology 2010
(Anoxia...) :
For instance, loss of
miR-149 , miR-200c and mir-141 causes gain of function of oncogenes ( KCNMA1, LOX ), VEGFA and SEMA6A respectively and
increased levels of miR-142-3p, miR-185, mir-34a, miR-224, miR-21 cause loss of function of tumor suppressors
LRRC2 , PTPN13, SFRP1, ERBB4, and ( SLC12A1, TCF21 ) respectively
Tang et al., Brain Res 2011
(Brain Neoplasms...) :
Conversely,
LRRC4 , as a glioma suppressor,
inhibited the endogenous expression of
hsa-miR-381 and decreased cell proliferation and tumor growth