Gene interactions and pathways from curated databases and text-mining

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EPHB2 — IL17D

Text-mined interactions from Literome

Owaki et al., J Immunol 2006 : Furthermore, it was demonstrated that STAT1 is important for IL-27 induced activation of ERK1/2 , but not p38 MAPK, and that IL-27 directly induces mRNA expression of growth arrest and DNA damage-inducible 45gamma, which is known to mediate activation of p38 MAPK
Kalliolias et al., Arthritis Rheum 2010 (Arthritis, Rheumatoid...) : IL-27 inhibited human osteoclastogenesis, suppressed the induction of NFATc1, down-regulated the expression of RANK and triggering receptor expressed on myeloid cells 2 ( TREM-2 ), and inhibited RANKL mediated activation of ERK , p38, and NF-kappaB in osteoclast precursors
Diegelmann et al., J Biol Chem 2012 (Colitis...) : IL-27 activates ERK and p38 MAPKs as well as Akt, STAT1, STAT3, and STAT6 in IEC