Gene interactions and pathways from curated databases and text-mining

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IL8 — STX1A

Text-mined interactions from Literome

Zhang et al., J Lab Clin Med 2001 (Escherichia coli Infections) : The results showed that anisodamine significantly suppressed Stx1 induced tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and IL-8 production
Thorpe et al., Infect Immun 2001 : Furthermore, Stx1 induces both IL-8 and GRO-alpha protein in a dose-response fashion, despite an overall inhibition in host cell protein synthesis
Gray et al., Toxicological sciences : an official journal of the Society of Toxicology 2008 : As observed for DON, ricin-, and Stx1 induced IL-8 expression was suppressed by the PKR inhibitors C16 and 2-AP as well as impaired in UK9M cells
Yamasaki et al., FEBS Lett 1999 : IL-8 production at the protein level was enhanced by Stx1 and Stx2, but not by the mutant Stx1