Gene interactions and pathways from curated databases and text-mining

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EGFR — IL1B

Text-mined interactions from Literome

Wan et al., Int J Mol Med 2001 (MAP Kinase Signaling System) : IL-1 beta activated epidermal growth factor (EGF) receptor in cultured human keratinocytes in a time- and dose dependent manner
Gray et al., Mol Pharmacol 2004 : However, neither inhibition of epidermal growth factor receptor (EGFR) activation with the tyrosine kinase inhibitor 4- ( 3-chloroanilino ) -6,7-dimethoxyquinazoline HCl ( AG-1478 ) or EGFR blocking antibody nor inhibition of extracellular signal regulated kinase/P-38 mitogen activated protein kinases with specific inhibitors blocked IL-1beta stimulation of MUC5AC mucin production