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EDN1 — F2R
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
EDN1
→
F2R
(reaction)
Rubio et al., Genomics 1999, Dowal et al., J Biol Chem 2006, Lambert et al., Science signaling 2008, Amatruda et al., Proc Natl Acad Sci U S A 1991, Ferguson et al., J Biol Chem 1986, Chen et al., Biochim Biophys Acta 1996
Text-mined interactions from Literome
Baker et al., FEBS Lett 2008
(Inflammation) :
Combining high-resolution fluorescence microscopy and functional assays, we found that
activation of the GPCRs
PAR-1 and ET ( A/B ) by their natural inflammatory mediator agonists, thrombin and
endothelin-1 , resulted in rapid and acute internalization of gap junctions ( GJs ) that coincided with the inhibition of GJIC followed by increased vascular permeability
Chen et al., Biochem Biophys Res Commun 1995
:
Endothelin-1 does not
induce thrombin receptor degradation nor change in thrombin receptor mRNA level after 2 h and 24 h of incubation