◀ Back to INS

INS — SOCS6

Text-mined interactions from Literome

Li et al., J Biol Chem 2004 : Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism ... Furthermore, SOCS-6 expression is transiently increased by serum and insulin in normal fibroblasts ... In contrast, SOCS-6 associated p85 was not degraded and could be recruited to the newly synthesized SOCS-6 molecules in the presence of insulin, suggesting that SOCS-6 expression and its interaction with p85, but not the degradation, is regulated by insulin
Hwang et al., Biochem Biophys Res Commun 2007 (MAP Kinase Signaling System) : In addition, we demonstrated that PMA, insulin , and PDGF increased both the stability of endogenous expressed SOCS6 and Erk activation in MDA-MB231 cells
Gupta et al., PloS one 2011 : Insulin-like growth factor-1 (IGF-1) stimulation which enhanced neurite outgrowth of neural cells resulted in further enhancement of SOCS6 expression