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Text-mined interactions from Literome

Li et al., Acta Pharmacol Sin 2006 (Pulmonary Disease, Chronic Obstructive) : To study the effects of N-acetyl-L-cysteine (NAC) and pyrrolidine dithiocarbamate ( PDTC ) on the phosphorylation of IkappaB kinase (IKK) beta, IKK alpha, and IkB alpha in alveolar macrophages ( AM ), and to explore the pharmacological mechanisms of NAC and PDTC as inhibitors of NF-kappaB activation ... NAC inhibited the phosphorylation of IKKbeta, IKK alpha, and IkappaB alpha induced by TNF-a, but had no effect on the phosphorylation of IKKbeta, IKK alpha and IkappaB alpha induced by IL-1
Spiecker et al., J Leukoc Biol 1998 : NAC inhibited IkappaB kinase (IKK) activity and prevented IkappaB-alpha phosphorylation and degradation