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STAT5A — TNF
Text-mined interactions from Literome
Klein et al., Shock 2003
(Burns...) :
The changes in cytokine profiles after burn, particularly interleukin-1beta and macrophage inhibitory factor, appear to be mediated by C/EBP-beta and STAT-3, whereas after the induction of a sepsis,
tumor necrosis factor and interleukin-6 are mainly
mediated by
STAT-5
Rehn et al., Acta Physiol Scand 2004
:
Staining of the ganglionic cells with an antibody against the transcription factor STAT5 revealed that
TNF-alpha induced a nuclear translocation of
STAT5 in non-neuronal cells
DiFedele et al., Gastroenterology 2005
(Carcinoma, Hepatocellular...) :
TNFalpha down-regulated GHR abundance and
prevented GH-induced tyrosine phosphorylation of
STAT5 in rat hepatocytes in culture
Ahmed et al., Am J Physiol Gastrointest Liver Physiol 2006
:
TNF attenuated
JAK2/STAT5 and ERK1/2 phosphorylation and IGF-I and Spi 2.1 mRNA expression following GH stimulation
Storz et al., FEBS Lett 1998
:
TNF inhibits insulin induced
STAT5 activation in differentiated mouse muscle cells pmi28 ...
TNF downregulated insulin induced insulin receptor kinase activity and insulin
induced activation of the transcription factor
STAT5