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MT3 — NFKB1

Text-mined interactions from Literome

Sakurai et al., FEBS Lett 1999 : Regulatory role of metallothionein in NF-kappaB activation
Hinata et al., Oncogene 2003 (Inflammation) : Levels of growth inhibitory factor (GIF) , in contrast, were increased by NF-kappa B in both settings but inhibited growth only in keratinocytes
Butcher et al., J Pharmacol Exp Ther 2004 : In fact, MT-KO cells had higher nuclear levels of NF-KappaB p65 than did MT-WT cells, despite a lower cellular NF-KappaB level and function, suggesting that metallothionein mediated the specific activity of NF-KappaB ... These data support the hypothesis that metallothionein positively regulates the cellular level and activity of NF-KappaB
Kim et al., Toxicological sciences : an official journal of the Society of Toxicology 2009 : The MT-III induced antiapoptotic effects and increase in NF-kappaB activity were blocked by specific inhibitors of TrkA, phosphatidylinositol-3 kinase (PI3K), Akt, or NF-kappaB, indicating that MT-III provides neuronal protection by activating NF-kappaB through the TrkA/PI3K/Akt signaling pathway