Gene interactions and pathways from curated databases and text-mining

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PIM1 — TRAF2

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: TRAF2 → PIM1 (increases, PIM1 Activity, TRAF2 Activity)
    Evidence: Fig. 2. Pim-1 is post-transcriptionally regulated by stabilization on the mRNA and protein level and degraded by PP2A.The phosphorylation by Pim-1 results in an inactivation of repressors or activation of transcription factors or regulatory proteins, in the stabilization of proteins, which are involved in signaling pathways and in the inactivation of pro-apoptotic proteins.