Gene interactions and pathways from curated databases and text-mining

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CSE — MUC7

Text-mined interactions from Literome

Baginski et al., Am J Respir Cell Mol Biol 2006 (Carcinoma, Mucoepidermoid) : We demonstrated that cigarette smoke extract (CSE) synergistically increased gene expression and protein production of MUC5AC mucin induced by LPS or TNF-alpha in human airway epithelial NCI-H292 cells ... CSE also enhanced expression and production of MUC5AC mucin induced by epidermal growth factor receptor (EGFR) ligands TGF-alpha and amphiregulin, as well as LPS- and TNF-alpha- induced expression and/or release of TGF-alpha and amphiregulin
Fan et al., The open respiratory medicine journal 2010 : In vitro treatment of cells with LPS ( 10 ( microg/ml ) or CSE ( 0.5, 1, 2.5 and 5 % ) alone, resulted in a statistically significant increase of MUC7 transcripts only with 1 % CSE ( 3.2-fold ) ... The combined CSE/LPS treatment resulted in a synergistic increase of MUC7 with 0.5 % CSE/LPS ( 4.4 fold )