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GDNF — NPY

Text-mined interactions from Literome

Anitha et al., Gastroenterology 2006 : We examined the effects of GDNF on the expression and release of NPY from enteric neurons and the role of NPY in promoting enteric neuronal proliferation and survival ... GDNF induced expression of NPY was assessed by reverse-transcription polymerase chain reaction ( RT-PCR ), immunocytochemistry, and enzyme linked immunosorbent assay ... GDNF induced a significant increase in NPY messenger RNA and protein expression in primary enteric neurons and the release of NPY into the culture medium
Choi et al., Development 2009 : NPY was also found to reverse the decreased budding, the downregulation of RET expression, the mislocalization of GFRalpha1, and the inhibition of AKT phosphorylation that resulted from the addition of BMP4 to the isolated WD cultures, suggesting that NPY acts through the budding pathway and is reciprocally regulated by GDNF and BMP4