Gene interactions and pathways from curated databases and text-mining

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ANG — PTEN

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Tsigkos et al., J Cell Physiol 2006 : Regulation of Ang2 release by PTEN/PI3-kinase/Akt in lung microvascular endothelial cells ... In addition, adenovirus mediated gene transfer of the phosphatase PTEN stimulated Ang2 release
Yu et al., Zhonghua Xin Xue Guan Bing Za Zhi 2006 (Cardiomegaly) : To investigate the effects of PTEN on Ang II induced cardiomyocyte hypertrophy and subsequent Ca ( 2+ ) /Calcineurin pathway changes
Dong et al., J Cell Biochem 2013 : This study shows that down regulation of PTEN expression and activity by angiotensin II (Ang II) increased proliferation and migration of vascular smooth muscle cells ( VSMCs )