Gene interactions and pathways from curated databases and text-mining

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KITLG — TNF

Text-mined interactions from Literome

Yan et al., Endocrinology 1999 : Activin, TGF beta, TGF alpha, and tumor necrosis factor-alpha had no effect on SCF gene expression in vitro
BrazĂ­s et al., Vet Immunol Immunopathol 2000 : Stem cell factor enhances IgE mediated histamine and TNF-alpha release from dispersed canine cutaneous mast cells ... However, we observed that SCF used as a co-stimulus significantly potentiated histamine and TNF-alpha release in canine MC activated through Fc epsilon RI regardless of whether or not SCF was added to the medium during culturing
Bouchelouche et al., J Urol 2006 : We investigated whether HDSMCs are capable of expressing and releasing MCP-1, IL-6 and SCF in response to IL-4, IL-13, IL-1beta and tumor necrosis factor-alpha ... Furthermore, IL-1beta and tumor necrosis factor-alpha alone induced significant release of MCP-1, IL-6 and SCF but in combination with IL-4 or IL-13 it induced greater secretion of MCP-1, IL-6 and SCF
Wong et al., Allergy 2006 : Either SCF or TNF-alpha could induce release from HMC-1 cells of interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, regulated upon activation normal T-cell expressed and secreted ( RANTES ), and I-309, while SCF and TNF-alpha induced release of macrophage inflammatory protein (MIP)-1beta and interferon-gamma-inducible protein-10 (IP-10), respectively
Kim et al., Toxicol Appl Pharmacol 2007 : In addition, production of tumor necrosis factor (TNF)-alpha , interleukin (IL)-1beta, and vascular endothelial growth factor ( VEGF ) production induced by SCF was significantly inhibited by treatment with SC-236
Ren et al., Surgery 2008 : In vitro studies using primary mouse hepatocytes show that SCF is induced by TNF-alpha ; anti-SCF antibody treatment in this system inhibits TNF-alpha induced hepatocyte proliferation, suggesting that TNF-alpha induced hepatocyte proliferation is also SCF dependent
Lin et al., Immunology 1996 : The effect of stem cell factor (SCF) on histamine and tumour necrosis factor-alpha (TNF-alpha) release from rat peritoneal mast cells ( PMC ) was determined and the intracellular pathways involved in the potentiation of histamine secretion were investigated
Brito et al., J Leukoc Biol 1997 (Granuloma...) : We have shown that the SCF expression can be induced in vitro by co-culture with mast cells and this induction was dependent on the release of tumor necrosis factor alpha (TNF-alpha)
Hogaboam et al., J Immunol 1998 : SCF was constitutively produced from fibroblasts in its transmembrane form and could be induced by TNF
Ishizuka et al., J Immunol 1998 : Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells