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PDLIM7 — TNF

Text-mined interactions from Literome

Haraguchi et al., AIDS research and therapy 2006 : LMP-420 , a small-molecule inhibitor of TNF-alpha , reduces replication of HIV-1 and Mycobacterium tuberculosis in human cells
Chuang et al., Am J Pathol 2007 (Disease Progression...) : LMP-1 up-regulated TNF-alpha through TRAF2,5 and nuclear factor-kappaB pathway in T cells
Li et al., Cancer Res 2007 (Breast Neoplasms...) : Similar to that of LAPF silencing, silencing of endogenous p53 expression in L929 cells could significantly impair TNF-alpha induced LMP and apoptosis
Hale et al., Journal of inflammation (London, England) 2008 : Treatment of experimental colitis in mice with LMP-420 , an inhibitor of TNF transcription
Mayanja-Kizza et al., Scand J Immunol 2009 (AIDS-Related Opportunistic Infections...) : LMP-420 , a small molecular transcriptional inhibitor of both TNF-alpha and MCP-1 expression, did not reduce MTB induced HIV-1 expression
Ullio et al., J Lipid Res 2012 (Carcinoma, Hepatocellular) : TNF/CHX induced LMP is effectively abrogated by siRNAs targeting acid sphingomyelinase or acid ceramidase, which prevent both LMP and death induced by TNF/CHX
Angaswamy et al., Cell Transplant 2012 : Using a murine model of ITx, we determined the role of LMP-420 , a novel TNF-a inhibitor , both individually and in combination with the immunosuppressant cyclosporine A ( CSA ) in islet engraftment and survival