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NOS1 — PC
Text-mined interactions from Literome
Sharma et al., Toxicol Appl Pharmacol 2002
:
Among the two selected dichloro PCBs, the
ortho-PCB , 2,2'-dichlorobiphenyl ( DCB ),
inhibited both cytosolic and membrane
NOS activity at low micromolar concentrations ( 3-10 microM ) in the selected brain regions of all age groups while the non-ortho-PCB, 4,4'-DCB, did not ... In summary, these results indicate that only
di-ortho-PCB inhibited both
NOS and hydroxy substitution of one or more chlorine molecules significantly increased the potency of both ortho- and non-ortho-HCBs
Yun et al., Toxicology 2005
(Neurotoxicity Syndromes) :
These results indicate that Vitamin E may have neuroprotective effects by inhibiting
PCB induced
nNOS phosphorylation