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MAPK1 — NTRK3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Tognon et al., Cancer Res 2001
(Cell Transformation, Neoplastic...) :
The chimeric protein tyrosine kinase
ETV6-NTRK3 requires both
Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation
Jin et al., Cancer Res 2007
(Cell Transformation, Neoplastic) :
Here, we define some aspects of the molecular mechanisms regulating
ETV6-NTRK dependent
Ras-Erk1/2 and PI3K-Akt activation
Jin et al., J Biol Chem 2008
(Cell Transformation, Neoplastic) :
Here we define some aspects of the molecular mechanisms regulating
TrkC dependent
Ras-Erk1/2 and PI3K/Akt activation
Weinkauf et al., Infect Immun 2009
(Chagas Disease) :
PDNF promotes
TrkC dependent
mitogen activated protein kinase signaling, neurite outgrowth, and survival of genetically engineered PC12 neuronal cells and glial Schwann cells in a TrkC dependent manner
Ivanov et al., Oncogene 2013
(Carcinoma, Adenoid Cystic...) :
NT-3 stimulation of U2OS cells with ectopic
TrkC expression triggered TrkC phosphorylation and
resulted in Ras,
Erk 1/2 and Akt activation, as well as VEGFR1 phosphorylation
Guiton et al., J Biol Chem 1995
:
In cells expressing full-length TrkC, neurotrophin-3 promoted a sustained activation of mitogen activated protein kinase ;
TrkC containing kinase inserts only mediated transient
activation of
mitogen activated protein kinase
Gunn-Moore et al., Biochem J 1997
:
Experiments with the use of cell-permeant inhibitors argue against a major role for PLC gamma and PtdIns 3-kinase in the
activation of
MAPK by
TrkC