Terragni et al., BMC cell biology 2008
:
Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors
Zhou et al., Gastroenterology 2009
(Colitis...) :
FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation ... Mechanistically, FoxO4 inhibited the transcriptional activity of nuclear factor-kappaB (NF-kappaB) , and Foxo4 deficiency is associated with increased NF-kappaB activity in vivo ... Mechanistically, FoxO4 inhibited the transcriptional activity of nuclear factor-kappaB (NF-kappaB) , and Foxo4 deficiency is associated with increased NF-kappaB activity in vivo